"Broksinak", eye drops: instructions, reviews, analogues

Nonsteroidal anti-inflammatory drugs are used not only in the presence of joint and muscle diseases, but also in other pathological conditions. Such drugs are designed to reduce pain and reduce the inflammatory process. Often they are used in ophthalmic practice after surgery.

One of the most popular means in this area is "Broksinak" - eye drops. Instruction, analogues, indications, side effects and contraindications of this drug will be presented below.

Form of release, description, composition and packaging of medicine

The medication "Broxinac" (eye drops), the instruction of which is contained in a box of thick paper, is a transparent solution of a greenish-yellow color. Its active ingredient is bromfenac sodium sesquihydrate.

It should also be noted that the droplets also contain auxiliary components, which are presented as boric acid, benzalkonium chloride, disodium edetate dihydrate, povidone K-30, polysorbate 80, sodium borate decahydrate, sodium hydroxide, sodium sulfite anhydrous and purified water.

In what kind of packaging can you buy a Broxinac solution? Eye drops go on sale in bottles placed in cardboard boxes.

Pharmacological properties

What is the Broxinac solution (eye drops)? The instruction (feedback on the effectiveness of the drug presented below) indicates that it is a non-steroidal anti-inflammatory agent that has analgesic and anti-inflammatory effects.

By inhibiting cyclooxygenase 2 and 1, said preparation is capable of blocking the synthesis of prostaglandins from arachidonic acid. As a result of this effect, inflammation decreases and pain is reduced.

Researches of experts have shown, that prostaglandins are mediators of some kinds of an inflammation in visual organs. During the experiments on animals, it was found that these substances contribute to the violation of the hemato-ophthalmic barrier, and also increase the permeability of the vessels, causing leukocytosis and vasodilation. Moreover, prostaglandins significantly increase intraocular pressure.

Kinetic features

Is the drug Broxinac (eye drops) absorbed? The instruction says that the concentration of this drug in the blood is much lower than the measurement limit. In this regard, it has no clinical significance.

According to experienced specialists, bromfenac penetrates well into the cornea. With a single use of the drug, its concentration in the aqueous humor of the visual organs is 79 ± 68 ng / ml. These values are observed after 155-180 minutes after instillation of the solution into the eyes. This concentration is maintained for 13-23 hours.

The half-life of bromfenac from watery moisture is approximately 1.4 hours.

Indications for the use of drops

Do you know about the purpose of the drug "Broxinac"? Eye drops are used to treat postoperative inflammations and to reduce pain in people after cataract extraction.

Contraindications

What conditions of the patient prohibit the use of the medication Broxinac (eye drops)? Instructions for use (according to the prescription of the doctor this drug can be purchased in almost any pharmacy in Moscow) informs about the following contraindications:

• Presence of hypersensitivity to solution substances, as well as to other NSAIDs;
• Urticaria, seizures of bronchial asthma and symptoms of acute rhinitis, which are intensified when taking NSAIDs or acetylsalicylic acid;
• Minor age (efficacy and safety of use of medication in children and adolescents have not been studied).

The sodium sulfite contained in the solution in susceptible people can cause an allergic reaction, including asthma attacks and anaphylactic shock. Therefore, this category of people prescribe the drug with extreme caution. It should also be noted that sensitivity to sulfites is increased in patients with an allergy in history and bronchial asthma.

It should also be noted that when using the agent in question, there is a possibility of developing a cross-sensitivity to derivatives of phenylacetyl acid, acetylsalicylic acid and other NSAIDs. In this regard, it is necessary to observe special care in the treatment of people who have previously manifested negative reactions to these drugs.

What other contraindications should you know before using the Broxinac solution (eye drops)? The instruction for use says that NSAIDs as a result of a violation of platelet aggregation can significantly increase bleeding time.

The use of local anesthetics in combination with ophthalmic operations promotes increased bleeding of the tissues of the visual organs (including the anterior chamber of the eye).

In connection with all of the above, it can be safely concluded that the drug in question should be used with extreme caution in people who have a history of a tendency to bleeding, and also if the patient is taking other drugs that increase clotting time Blood.

As medical practice shows, the use of local NSAIDs in patients with corneal denervation, complications after eye surgeries, corneal epithelial defects, rheumatoid arthritis, diabetes mellitus, superficial eye diseases or repeated surgical interventions that have been carried out for a short period of time may Significantly increase the risk of developing undesirable effects from the cornea.

The drug "Broxinac" (eye drops): the instruction

How and in what dosage do they install the drug in the conjunctival sac? According to the instructions, this medicine is used one drop per day.

As a rule, the therapy is started one day before the surgery and is continued during the first two weeks of the postoperative period (including the day of the operation).

What should I do if the patient misses the procedure of instillation with Broxinac? Eye drops, reviews of which are ambiguous, should be used as soon as possible in the dose prescribed by the instruction.

In the event that it has been 20-24 hours, the drug should be digested at the next scheduled time. It is forbidden to double the dose in order to compensate for the missed dose.

The method of administration and dosage of the solution for treating patients older than 65 years does not differ from the method of administration and dosage in younger people.

Undesirable reactions

What side effects occur when using the Broxinac solution? Eye drops, the instruction of which was presented above, with a single application can cause the following reactions:

• Erosion of the cornea, thinning and perforation of the cornea, destruction of the epithelium;
• Severe and frequent headaches;
• Unusual sensations and a feeling of discomfort in the eyes, burning and itching, irritation, redness and pain, inflammation of the iris, congestion hyperemia;
• Decreased visual acuity, corneal edema, retinal hemorrhage, bleeding from eyelid vessels, photophobia, exudates on the fundus;
• Nosebleeds, nasal discharge, cough, asthma;
• Corneal ulcer;
• Swelling of the face.

Signs of an overdose

What if the patient accidentally ingested Broxinac? Eye drops, photos of which you can find in this article, are intended only for topical application. If you drink medication inside, you should immediately drink plenty of water. This is necessary in order to reduce the concentration of the drug in the stomach.

Compatibility with other medicines

The drug is allowed to be used simultaneously with other ophthalmic agents, including alpha-adrenomimetics, beta-adrenoblockers, mydriatics and inhibitors of carbonic anhydrase. In this case, all listed medicines should be applied with an interval of 5 minutes.

Pregnancy and lactation

Can I use the drug Broxinac during pregnancy? Eye drops, the synonyms of which are indicated below, can be used during the gestation, but only if the expected effect for the future mother will exceed the likely risk for the baby.

It should also be noted that it is necessary to avoid the appointment of drops during late pregnancy.

With special care, this medication is recommended to women during breastfeeding.

Special Recommendations

Use of local NSAIDs a day before the operation before the eyes and within two weeks after ophthalmic intervention may increase the risk of development and severity of unwanted reactions from the cornea.

Burying nonsteroidal drops contributes to the formation of keratitis.

In susceptible people, continued use of local NSAIDs can cause a rupture of the epithelium, as well as thinning, erosion, perforation of the cornea and the formation of ulcers on it. Such side effects create a risk of vision loss.

People with symptoms of corneal epithelial rupture should immediately stop using the solution and consult an experienced ophthalmologist.

The use of NSAIDs can inhibit healing processes, especially when combined with local corticosteroids. Patients should be sure to inform about this feature of the medication.

When using the Broxinac solution, do not wear contact lenses.

Patients should be warned that they do not touch the tip of the dropper bottle with their fingers, nor do they touch any other surface, including the mucous eyes. Otherwise, it can lead to contamination of the medicine.

The drug in question only slightly affects the ability of a person to drive vehicles and manage dangerous mechanisms. After instillation of the solution, the patient may be briefly blinded by vision. In this regard, it is recommended to wait a little, that it is fully restored.

The drug "Broxinac" (eye drops): analogues and cost

There is no synonym for this remedy. However, if necessary, it can be replaced by analogues such as Diclofenac, Cetadrope, Voltaren Ophta, Uniklofen, Diklo-F, Diclofenaclong, Nevanak, Akular, Indocollir.

As for the cost, the average price of the eye drops we are considering is 370-420 rubles.

Customer Reviews

Most people leave only positive reviews about this drug. According to their opinion, the drops of "Broxinac" effectively cope with the task. As a rule, they are appointed after surgery on the eyes. Reviews say that the use of the drug helps reduce the inflammatory process and reduce pain.

However, often against the background of the application of these eye drops in patients, there are adverse reactions, including those dangerous for the eyesight. In this case, the medicine must be canceled independently and immediately go to the ophthalmologist.

It should also be noted that this drug has other disadvantages. Patients refer to them a high cost. In addition, people constantly complain that it is rather difficult to find such a tool in small Russian cities. Often it has to be ordered via the Internet.