"Adenorm": instructions for the use of the drug

What is the medication for Adenorm? Instructions for using the drug and its readings are listed below. Also in this article you will find information on the form in which this product is put on the market, what patients are talking about and how it can be replaced with an analogue.

Composition of the drug, its description and form

In what form is produced such a tool as "Adenorm"? Instructions for use say that this drug can be purchased in the form of solid white-yellow capsules. The active component of this drug is tamsulosin hydrochloride. As additional components use spherical sugar, hydroxypropylmethylcellulose, ethyl cellulose, hypromellose phthalate, povidone, diethyl phthalate, talc and cetyl alcohol.

As for the hard gelatin capsule, it consists of the dye of indigotine, iron oxide yellow, iron oxide red, gelatin and titanium dioxide.

Pharmacological features

In what cases do you use Adenorm? Instructions for use asserts that this remedy is often prescribed for hyperplasia of the prostate gland (benign type).

This medication refers to antagonists of alpha 1-adrenergic receptors located in the smooth musculature of the gland of the prostate, prostatic part of the urethra, and also in the body and neck of the bladder. Due to the effect of this agent, their tone is reduced.

One can not help saying that this drug improves the work of detrusor, contributes to the elimination of symptoms of irritation and obstruction, which are manifested due to hyperplasia of the prostate gland.

How quickly does the drug "Adenorm"? Instruction for use reports that the effectiveness of this drug is noticeable after two weeks after the start of treatment. In this case, a decrease in the manifestations of the disease can be seen in the first days of the course.

Pharmacokinetic properties

For the drug "Adenorm," which reviews are only positive, linear kinetics is characteristic. Its active substance is rapidly absorbed from the intestine. The greatest plasma concentration of the drug after taking one dose of 0.4 mg is observed after 6 hours. In this case, a fairly strong bond with proteins arises.

According to the instructions, this medication is very slowly broken down in the liver (inactive derivatives are formed). The main part of the active element is present in the human body in an unchanged form.

With a single dose of 0.4 mg, the half-life of the drug is 10 hours, and with prolonged use, approximately 12 hours.

From the body the medication is excreted by the kidneys in the form of derivatives (about 9% of the drug is excreted unchanged).

Indications for taking capsules

The drug "Adenorm," whose analogs are listed below, are used to treat disorders of the urinary tract (lower), including in the presence of prostate hyperplasia (benign type).

Contraindications to the reception of gelatin capsules

In what cases is it forbidden to prescribe Medication Adenorm? Instructions for use, reviews argue that this drug should not be used with increased sensitivity to its ingredients, as well as when treating patients with impaired liver function (severe).

In addition, the drug in question is not prescribed for people with orthostatic hypotension in history.

This drug should be used with extreme caution by those who suffer from abnormalities in the work of the kidneys (including a QC less than 10 ml / min). In addition, capsules "Adenorm" is not recommended to appoint patients whose activities are related to driving or potentially dangerous mechanisms. Otherwise, the work should be abandoned.

Medication Adenorm: instructions for use

The agent in question is taken orally. The hard capsule should be swallowed in its entirety, not crushing and not chewing, with plenty of water.

The drug is consumed regardless of the meal. The duration of the course of treatment, as well as the dosage of the drug is determined by the attending physician, in an individual order for each patient.

As a rule, for adults, the medication "Adenorm" is prescribed one capsule once a day.

People with minor disorders in the work of the liver or kidney dose adjustment is not required. As for patients with severe problems in this area, the rationale for taking and dosage of this drug is determined by the attending physician, taking into account the general clinical picture.

Occasional phenomena

When accepting the means under consideration, the following negative consequences are possible:

• Development of rhinitis;
• Headaches, dizziness;
• Rash on the skin, itching and hives;
• Hypotension orthostatic, palpitation;
• asthenia.

In rare cases, patients develop: syncope, Stevens-Johnson syndrome, constipation, angioedema, nausea, retrograde ejaculation, diarrhea, priapism, vomiting.

It should also be noted that there are cases of intraoperative instability of the iris of the visual organs during surgery for cataract in people who have been taking drugs for a long time with tamsulosin as an active substance.

Cases of overdose

Now you know the features of such a drug as "Adenorm". The description of the preparation was also presented above.

When an overdose of this drug in patients can dramatically decrease blood pressure. In this case, supportive therapy should be used to normalize the work of the CAS. Also, sometimes infusion treatment is performed and vasopressor drugs are prescribed.

When taking the drug, it is necessary to follow the work of the kidneys, and if necessary, to conduct general supportive therapy.

In case of excessive overdose, this agent should be used to induce vomiting, rinse the stomach and prescribe to the patient laxatives and activated charcoal.

Interaction with other drugs

The joint administration of the drug in question with other alpha1-adrenoblockers enhances its antihypertensive effect.

When the capsules are combined with "Cimetidine", the concentration of the active substance "Adenorma" increases, and with "Furosemide" - decreases. Although at the same time its level almost always remains within normal limits, therefore, it is not necessary to correct the dose in such cases.

Such NSAIDs as Warfarin and Diclofenac may increase the rate of excretion of Adenorm from the patient's body.

Together with the strong inhibitors of CYP3A4 and CYP2D6, the increased doses of the agent in question are unacceptable or taken with extreme caution.

Cost and analogy

The price of the medication "Adenorm" is about 360-400 rubles. If required, this drug is replaced by such means as "Hyperprost", "Tamsulosin" or "Omnik".

Reviews

As a rule, the given drug is prescribed by urologists after the patient undergoes ultrasound of the prostate and blood donation to the PSA. The admission of this remedy is allowed only if the patient has appropriate indications.

Consumers argue that the drug "Adenorm" is coping well with its task. Although some of them complain that it causes such side effects as persistent headaches and a feeling of palpitations.