Health, Preparations
What is "Ranitidine" taken from? Treatment of heartburn and stomach ulcers with the help of "Ranitidine"
What is "Ranitidine" from? Before answering the question, it is necessary to find out what the given preparation is, what composition it has, how it should be taken and in what dosages?
General information
What is "Ranitidine" from? This synthetic drug is an antiulcer drug that is able to significantly reduce the volume of gastric juice.
Composition of the medicament and its form of release
The drug "Ranitidine" is available in the following dosage forms:
- Tablets that contain 300 mg and 0.15 g of the active ingredient (ranitidine in the form of hydrochloride). This medication goes on sale for 100, 30 or 20 pieces in a carton.
- Injection. Such a drug is used only when the oral use of the drug for some reason is impossible. The medicinal solution goes on sale in ampoules of 2 ml.
Pharmacodynamics
Why is Ranitidine so often prescribed by doctors? Such a drug, or rather its active ingredient, rather quickly reduces the amount of gastric juice, the release of which is caused by the dilatation of the main digestive organ. Typically, this pathological condition is due to excessive nutritional load, and also under the influence of some biogenic stimulants (histamine, acetylcholine, gastrin, pentagastrin and caffeine) and hormones.
After using the drug "Ranitidine" in the patient, the mucosa of the main digestive organ is strengthened, and the amount of hydrochloric acid in its juice decreases markedly. It should be specially noted that with the use of this drug, the production of mucus practically does not change and the enzymatic functions of the liver are not suppressed.
"Ranitidine" medication promotes the healing and recovery of all damages of the gastric mucosa, which are associated with exposure to hydrochloric acid. This effect of the drug is due to an increase in the formation of mucus of the stomach. According to the instructions, the medicine "Ranitidine" in a dose of 0.15 g suppresses the secretion of the juice of the main digestive organ for 8-13 hours.
What is "Ranitidine" from?
Such a drug is used for the following abnormalities:
- Ulcers of the duodenum and stomach (especially in the stage of exacerbation);
- Inflammation of the esophagus, which is caused by throwing into it the contents of the stomach (with reflux-esophagitis);
- Inflammation of the esophagus due to a violation of the integrity of its mucosa (with erosive esophagitis) ;
- With symptomatic and rapidly developing ulcers of the duodenum and stomach, resulting from stress, taking certain medications or certain diseases of internal organs;
- Gastric ulcers in combination with a benign pancreatic tumor (with Zollinger-Ellison syndrome).
Application for prevention
The drug "Ranitidine" from the stomach is taken not only for treatment, but also for the prevention of the following abnormalities:
- Exacerbations of ulcerative and erosive diseases;
- Lesions of the upper parts of the digestive tract;
- Ingestion of gastric juice in the respiratory tract during surgical intervention (under anesthesia).
Contraindications for use
Tablets from the stomach "Ranitidine" should be taken only after consultation with the doctor. After all, this drug has some contraindications:
- pregnancy;
- In childhood (up to 14 years);
- Hypersensitivity to medication;
- Lactation period.
Also, the drug "Ranitidine" is prescribed with extreme caution in cases of violations of excretory work of the kidneys.
Dosage and methods of administration
The presented drug is prescribed in a given dosage depending on the diagnosis:
- If the ulcer of the duodenum or stomach is exacerbated, the medication is prescribed for the 1st pill twice a day or 0.3 g for the night. If urgently needed, the daily dosage of the agent can be increased to 400-450 mg.
- For the prevention of ulcers of the duodenum or stomach, the drug is prescribed at 0.15 g immediately before bedtime (once a day).
- In Zollinger-Ellison syndrome, this drug in an initial dose is prescribed in the amount of 1 tablet three times a day. In case of acute necessity, the named amount of the drug can be increased to 0.7-0.9 g per day.
- When ulcers occur after surgery, the drug "Ranitidine" is recommended to take 0.15 g twice daily. As a rule, healing takes place during the next 4 weeks.
- To prevent stress sores, the drug is prescribed 2 tablets twice a day.
- Tablets "Ranitidine" for heartburn is recommended to take in the amount of the first thing twice a day.
To prevent stress ulceration and bleeding, the drug "Ranitidine" should be used intramuscularly or intravenously for 0.1 or 0.05 g every 7-8 hours.
Side effects
This drug can cause the following side effects:
- skin rash;
- dizziness;
- Thrombocytopenia;
- headache;
- fatigue.
In rare cases, the medication "Ranitidine" provokes hair loss. Also, the drug presented can lead to hallucinations and the development of confusion. With prolonged intake of large doses, the patient increases the prolactin content, there is gynecomastia, leukopenia, impotence, amenorrhea and decreased libido. Sometimes, the use of such a drug can lead to the development of hepatitis.
special instructions
- This drug with extreme caution is prescribed to patients with severe renal or hepatic impairment.
- Before starting treatment with this remedy, the possible presence of a malignant disease of the stomach, esophagus or duodenum should be ruled out.
- In case of acute necessity of termination of therapy, the medicine is canceled by gradually decreasing the dose.
- The effectiveness of preventive use of the drug courses for 50 days in the autumn-spring period is much higher than when it is constantly taken.
Analogs means
"Zantak", "Rantak", "Ranisan", "Acilok", "Ulran", "Ulkodin", "Ranigast" and "Ranitidine-Akos" are the analogues of this medication. What are all these funds taken from? They contain the same active component, and therefore the indications for such drugs are identical.
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