HealthPreparations

The drug "Novirin": instructions for use, analogues and reviews

The production of antiviral drugs is gaining momentum. Scientists and pharmacists of advanced research centers are trying hard to find new effective substances for fighting insidious diseases, which bring irreparable harm to our health. One of the most modern antiviral drugs is Novirin. Instructions for use, features of the application, reviews of doctors and patients, as well as side effects from taking this medication, we will consider in this article.

In what form is it produced and what is the composition of the drug?

The tablet drug "Novirin" is packed in blisters of 10 pieces and placed in cardboard packages of 2 or 4 plates.

One tablet of a pharmaceutical agent comprises:

  1. The main active ingredient is inosine pranobex in the amount of 500 mg.
  2. Additional components: potato starch, as well as magnesium stearate.

How does the drug work?

This pharmaceutical product has a direct effect against pathogenic viruses. The drug "Novirin" includes a complex compound of molecules of inosine: N, N-dimethylamino-2-propanol: p-acetamidobenzoic acid in a proportion of 1: 3: 3, respectively. These substances bind to ribosomes contained in cells infected with viruses. As a result, the processes of i-RNA synthesis, replication of RNA and DNA of pathogens slow down. In other words, viruses stop multiplying and die. The complex of active substances of the drug was called inosine pranobex. He clinically proved his antiviral and immunomodulating effectiveness.

The drug "Novirin" reviews doctors and patients is positive. Experts note the versatility of its action:

  • Increases the synthesis of interferon;
  • The activity of T-lymphocytes and phagocytic action of macrophages increase;
  • Causes the isolation of pre-T-lymphocytes;
  • Intensifies the proliferation of B- and T-lymphocytes;
  • Increases the effectiveness of T-lymphocytes to produce lymphokines;
  • The proportion in which there are T-helpers and T-suppressors is normalized;
  • Increase in the formation of 1 and 2-interleukins;
  • The activity of NK cells is regulated;
  • The phagocytosis capacity of macrophages increases;
  • Growth of cells producing antibodies.

Taking Novirin with viral herpes accelerates the formation of antibodies, reduces clinical manifestations of the disease and reduces the frequency of relapses. In infected cells, the active complex of the drug prevents the reduction of RNA synthesis, reducing the burden on the patient's body, and supports its immunity.

After "Novirin" (tablets) was used by the patient, it is quickly absorbed and exhibits a high degree of bioavailability. For half an hour the antiviral effect begins, which lasts up to 6 hours. Peak concentrations of the drug are detected after 60 minutes. From the moment of taking the medicine. Inosine is metabolized by the scheme of purine nucleosides. It does not accumulate and is excreted from the human body in an unchanged form and in the form of derivatives in completely 48 hours.

At what diseases is the drug shown?

"Novirin" (tablets) is prescribed for patients with diseases of the viral nature, regardless of their immune status. The attending physician may prescribe the drug with the following ailments:

  • Influenza and parainfluenza.
  • ARVI.
  • Viral bronchitis.
  • Infections associated with rhinovirus and adenovirus.
  • Measles.
  • Endemic parotitis.
  • Herpes in various forms.
  • Panencephalitis.
  • Smallpox chickenpox.
  • Genital herpes zoster.
  • The Epstein-Barr virus.
  • Cytamegalovirus.
  • Viral hepatitis B.
  • Human papillomavirus.
  • Chronic diseases of the respiratory and genitourinary system with relapses in persons with weakened immunity.

As you can see, the list of indications is quite large, which makes this drug in demand with a fairly large range of diseases.

How should I apply the medicine?

In the question of how to correctly take Novirin, the instructions for use give the following recommendations:

  1. Tablets should be taken orally after meals, washed down with water or dissolved in a small amount.
  2. Observe the same breaks between taking the drug.
  3. For maximum effectiveness, you should begin treatment with this remedy when you show the first symptoms of the disease.
  4. The duration of the course and the dosage of the medicine is prescribed by the doctor, according to the patient's condition, his age, the type of infection, the nature of the therapy and the degree of drug tolerance.
  5. The maximum permissible dose of "Novirin" for adult patients is 8 tablets per 24 hours, which corresponds to 4 g of inosine pranobeksa.
  6. The drug can be taken alone or as part of a comprehensive treatment.

The course of treatment with this pharmaceutical agent is usually from 5 to 14 days. But in some cases, on demand, the doctor recommends a second appointment after a break of 7-10 days. The admissible duration of the drug "Novirin" application instruction calls a period of 6 months with the recommendations on the cycles of admission and rest between them.

As it was said earlier, the dosage of the medicine and the duration of its administration are prescribed by the doctor taking into account the peculiarity of the disease and the patient's condition. The advantage of this pharmaceutical product is the acceptability of Novirin for children older than 1 year. Patients note an excellent combination of efficacy - harmlessness, characteristic for this medication.

Dosage and duration of course for various diseases

In cases of acute respiratory viral infection, influenza and parainfluenza, this medication is prescribed:

  • Adults - 2 tablets three or four times in 24 hours, lasting 5-7 days.
  • Children - in a dosage of 50 mg / kg of weight for 24 hours, breaking this number into 3-4 fractional doses. Duration of taking the drug varies from 5 to 7 days.

The most common symptoms of the disease subsided for 3-5 days from the beginning of treatment with the drug, but it is necessary to bring the course to the end. If the doctor deems it necessary, then you can repeat the therapy after a break in a week.

In the treatment of viral bronchitis with Novirin, the instructions for use give the following recommendations:

  • Adults should drink 2 tablets three times a day for 2-4 weeks.
  • At the same disease, "Novirin" for children is prescribed in the amount of 50 mg / kg of weight, divided into 3 or 4 doses. Treatment also lasts from 2 to 4 weeks.

In the case of mumps inoculation of mumps, pranobeks is administered in an amount of 70 mg / kg body weight. This dosage is divided into 3-4 doses per day. Treatment lasts 7-10 days.

If a patient has measles, Novirin is prescribed at a dosage of 100 mg / kg of body weight. The amount of the drug is divided into 3-4 servings, the reception is carried out at equal time intervals. The duration of such therapy can be from 7 to 15 days.

With aphthous stomatitis, the drug "Novirin" is also prescribed. The medicine is applied on the following recommendation:

  • Children should consume inosine pranobeks in an amount of 70 mg / kg of body weight, dividing into 3 or 4 equal parts. After 6-8 days, the dosage of the drug is reduced to 50 mg / kg of weight, which are taken three times or four times a day twice a week by a course of 49 days.
  • Adults should drink 2 tablets of the drug "Novirin" 4 times in 24 hours. The length of treatment should be 6-8 days. After this period, the dosage is reduced to 2 tablets three times a day twice a week for a course of 42 days.

If the patient has a cytomegalovirus infection or a mononucleosis, then he is recommended to treat Novirin in an amount of 50 mg / kg of body weight. This dosage is proposed to be divided into 3 or 4 equivalent doses in 24 hours. The duration of therapy for cetamegalovirus disease ranges from 25 to 30 days, with mononucleosis - 8 days.

In the treatment of herpetic infection of various locations and shingles, Novirin is also prescribed. It is recommended to use it according to the following scheme:

  • Adults should drink 2 tablets of medicine 3 or 4 times a day for 10-15 days. If a patient has genital herpes, then inosine pranobex should be taken 2 tablets 3 times for 24 hours 5-6 days with exacerbation. At the end of this period, you should drink 2 tablets in 24 hours. Supportive treatment for this disease lasts up to 6 months.
  • Children dosage of the drug is calculated in a ratio of 50 mg / kg weight. This number should be taken per day, divided into 3 or 4 equal parts. The course of therapy also ranges from 10 to 15 days.

In the case of subacute sclerosing encephalitis, Novirin should be taken at a dosage of 50-100 mg / kg of the patient's weight. The received amount is divided into 6 equal parts and taken for a day at the same intervals for 8-10 days. At the end of this period, take a break and repeat the course. According to the severity of the disease, the doctor can prescribe from 2 to 10 therapeutic periods of treatment with inosine pranobex.

If the patient has identified diseases associated with human papillomavirus infection, he is prescribed to drink 2 tablets of the drug "Novirin" three times a day, with a course of 14-28 days. After the patient was given CO2 laser therapy or cryodestruction, he continues to drink 2 tablets of this drug three times a day for 5 days. Usually recommend to spend 3 courses, between which make a break lasting a month.

When treating hepatitis B with the drug "Novirin" adults should use 2 tablets of the drug 3 or 4 times a day for 15 to 30 days. At the end of this period, the patient is advised to switch to 2 tablets in 24 hours. Continue this treatment can be from 3 to 7 months.

In the presence of patients with reduced immunity of chronic diseases of the urogenital and respiratory system, the use of the drug "Novirin" deserves a positive review. Doctors in the circumstances recommend taking the drug as follows:

  • Adult patients drink 3 or 4 times a day tablets in the amount of 2 pieces 2-12 weeks.
  • Children drink the drug in the amount of 50 mg / kg of weight, dividing the dose into 3 or 4 doses per day. Continue treatment should be 3 weeks. You can also give "Novirin" (tablets) to children in periods of 7-10 days, between which a rest of the same duration is arranged.

This medicine showed excellent results in correcting the weakened immunity of patients of the older and younger age group. The best recommendations for the reception of the pharmaceutical Novirin - reviews. To children, this drug significantly helps to increase resistance to viral infections. Doctors say that taking prenobex inosine lasting from 3 to 9 weeks helps to achieve a stable immunomodulating index in patients.

Features of the drug

If elderly patients require an antiviral agent for treatment, Novirin is suitable for this. In addition, correction of the dosage of the active substance is not carried out. However, it is worth noting the need for careful monitoring of the uric acid in the blood of the patient throughout the course of treatment.

If the doctor prescribes a continuous intake of this pharmaceutical product, the following indicators need to be monitored in laboratory control:

  • Functional activity of the liver;
  • Concentration of uric acid in biological fluids;
  • Indicators of peripheral blood;
  • Kidney function.

Does Novirin have side effects?

Doctors say that the drug "Novirin" (pills) reviews patients is positive and is usually tolerated, even with prolonged use. However, there are some side effects that need to be told.

The most frequent undesirable consequence of Novirin therapy is a short-term reversible increase in the uric acid index in the patient's biological fluids. This effect is explained by the peculiarity of the metabolism of inosine pranobex. At the end of the course of treatment, this indicator returns to the limits of physiological norm in a couple of days.

During the clinical trials of Novirin, other side effects were also found:

  • Great fatigue, weakness, headache, nervousness, dizziness, sleep disorder.
  • Nausea, vomiting, stool, pain over the peritoneum, an increase in the level of digestive enzymes.
  • Rashes on the skin and itching, hives, Quincke can develop swelling.
  • The growth of urea nitrogen in the blood, polyuria, arthralgia.

If these symptoms occur, consult a doctor. Treatment with this medication should be stopped until further advice from a medical professional.

Contraindications

Before taking Novirin, you should carefully read its composition. If the patient has an increased sensitivity to the main and auxiliary components of the drug, then it is worth immediately telling the medical specialist. In these cases, the drug is replaced by an analogue or a synonym - at the discretion of the doctor.

Among the contraindications to the reception of "Novirin" there are also the following positions:

  • Severe renal insufficiency;
  • gout;
  • Hyperuricemia;
  • Age up to 1 year;
  • urolithiasis disease.

With caution should be appointed "Novirin" the following group of patients:

  • Sick of the elderly.
  • Presence in the anamnesis of indications on hyperureukemia, dysfunction of kidneys, gout and urolithiasis.

If under the circumstances, treatment with inosine pranobex was still prescribed, then it should be accompanied by mandatory monitoring of uric acid in the patient's urine.

Can "Novirin" be pregnant?

The study of the action of inosine pranobex on the body of pregnant women was not carried out, therefore, there is no relevant data. "Novirin" in this period, women are not appointed. It is also undesirable to take the drug during breastfeeding.

Does the drug interact with other drugs?

The drug "Novirin" is a medicine that is prescribed with caution, together with inhibitors of xanthine oxidase ("Allopurinol"). The increased attention should be shown at joint treatment with medicines which strengthen allocation of uric acid together with urine. To such medicines it is possible to carry tiazidnye or loop diuretics.

Can an overdose occur?

In medical practice, as well as in clinical trials of Novirin, cases of overdose were not observed.

Theoretically, this phenomenon can occur when taking the drug in a dosage exceeding the recommended one. In this case, the patient may experience an increase in the level of uric acid in biological fluids. In such cases, the patient is recommended gastric lavage and therapy against intoxication of the body.

Are there analogues?

In certain situations, when the patient has contraindications to taking Novirin, analogues can be prescribed by the doctor as an alternative. Such drugs are considered pharmaceuticals that have antiviral and immunomodulatory therapy analogs of this pharmaceutical. To them it is possible to carry:

  • "Engystol";
  • Umkalor;
  • "Marimer";
  • "Immunal";
  • "Immupret";
  • "Ascotsin";
  • "Geviran";
  • "Lymphomyosot";
  • Tamiflu;
  • "Acyclovir" and other drugs.

However, it is only a qualified medical specialist who should decide whether to accept the patient better - Novirin, its analogues or synonyms.

In conclusion, it should be noted that the information on Novirin, given in this article, is a simplified version of the instruction. The appointment of treatment with this medicine, dosage and duration of the course is prescribed only by the attending physician.

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