Progesterone: injections

Progesterone is the hormone of the yellow body, which exerts a gestagenic effect. Through communication in target organs with receptors of cell surfaces, it penetrates into the nucleus, stimulates RNA, activating DNA. Under the influence of progesterone, the uterine mucosa passes from the proliferation stage, provoked by the follicular hormone, into the secretory stage. After fertilization, the hormone creates optimal conditions for implantation and further development of the ovum (fertilized). In addition, it (progesterone) reduces the excitability and contractility of the uterine musculature and muscles of the tubes, stimulates and develops in the mammary gland the terminal elements.

By stimulating the protein lipase, the fat storage and glucose utilization increase, the concentration of stimulated and basal insulin increases, glycogen begins to accumulate in the liver, and the production of aldosterone increases. Small doses of progesterone accelerate, and large suppress the production of gonadotropic hormones in the pituitary gland. Activation of the growth in the mammary glands of the acinus secretory department is induced, lactation is induced, normal development of the endometrium is stimulated.

Progesterone: injections. Instructions

The drug is prescribed for amenorrhea, endocrine infertility (including with a deficiency of the yellow body), anovulatory metrorrhagia, when there is a threat of abortion. Progesterone (nyxes) is also shown in algodismenore (against hypogenitalism), oligomenorrhea, in the diagnosis of the formation of endogenous estrogens.

Intramuscularly appointed with bleeding against a background of dysfunction of the ovaries daily from five to fifteen mg. Treatment lasts six to eight days.

In the case of scraping of the uterine mucosa, injections begin after eighteen or twenty-four days (if the scraping is not possible, the injection is made with bleeding). During treatment, a temporary increase in bleeding (for three to five days) is possible, after its cessation therapy continues for another six days. If after this period the condition is not relieved, further use of the drug is inappropriate.

With amenorrhea and hypogenitalism, Progesterone (injections) is administered daily at 5 mg or every other day at 10 mg. Therapy is carried out six to eight days (after using estrogenic drugs).

Treatment for algodismenore begins before the onset of menstruation in six to eight days. Daily injected at 5 or 10 mg, and so for six to eight days. If this disease is caused by uterine underdevelopment, estrogens are used (10,000 units a day for two to three weeks), then for six days - Progesterone medicine (injections).

In therapy or to prevent a beginning and threatening miscarriage, the drug is administered daily at twelve and a half milligrams for two weeks from the time of ovulation (if necessary, before the eleventh week of gestation) against a yellow body.

When diagnosing the formation of endogenous estrogen, 100 mg are administered once.

Throughout the duration of the use of the drug "Progesterone" (injections) it is recommended to be cautious with activities related to the increased concentration of attention and the speed of psychomotor reactions.

The drug is able to reduce the intensity of the effects of medications that stimulate smooth muscles in the uterus, anabolic steroids. The simultaneous use of barbiturates reduces the effect of the drug Progesterone.

The drug should be phased out gradually. The use of medication is controlled by the attending physician. The specialist should familiarize the patient with possible side manifestations and contraindications to the drug.