Medicinal product "Trimedat". Instructions for use

The drug "Trimedat" instructions for use refers to the group of antispasmodics. It is produced in the form of tablets, each containing two hundred milligrams of tri -butine maleate, the main active ingredient. Among the auxiliary components are: corn starch, talc, lactose, colloidal silicon dioxide, magnesium stearate.

Tablets are painted white, their shape is round, biconvex, on one side there is a risk.

Active active substance of the drug - trimebutin - regulates intestinal peristalsis, affecting its enkephalinergic system. This component also acts as a stimulant in the case of hypokinetic states of the smooth muscles of the intestine, and spasmolytic - in hyperkinetic.

The drug "Trimedat", the instruction informs, exerts its influence on the entire gastrointestinal tract, reduces the pressure on the sphincter of the esophagus. The medication also favors the activation of intestinal peristalsis and promotes the rapid painless emptying of the stomach.

Trimebutin is able to restore the normal natural activity of the musculature of the intestine for various diseases localized in the digestive tract, which are associated with malfunctions of motor activity.

The maximum content of the drug in the blood is reached after a lapse of one or two hours after oral administration. Bioavailability fluctuates within four to six percent. It is noted that the active ingredient of the medicament is able to penetrate insignificantly through the fetoplacental barrier.

Trimebutin passes the process of biotransformation in the liver, is excreted together with urine, mainly in the form of metabolites (with seventy percent of them leaving the body during the first day). The half-life is twelve hours.

The medicine "Trimedat" is indicated for use in the following cases:

• With motor disorders accompanying functional gastrointestinal diseases ;
• For the treatment of gastroesophageal reflux disease ;
• With dyspeptic disorders, which are symptoms of gastroduodenal diseases;
• For the treatment of irritable bowel syndrome, which is a functional disease of the gastrointestinal tract, accompanied by spasms, colic and discomfort in the abdominal cavity, bloating, stool disorder;
• With paralytic intestinal obstruction after surgery;
• In the period of preparation for endoscopic or roentgenological studies of the stomach.

Tablets "Trimedat" for children are used for dyspeptic disorders caused by a violation of the gastrointestinal tract.

The considered pharmaceutical product is contraindicated in case of hypersensitivity to the substances included in its composition. In addition, the medication in this dosage form is not assigned to patients under the age of twelve.

The drug "Trimedat" (the instruction draws special attention to this) should not be used for therapeutic purposes in the first trimester of pregnancy. In addition, it is not prescribed during the whole period of breastfeeding, as there is no reliable clinical information confirming the safety of taking the medication during this period.

Medicinal product "Trimedat". Instructions for use

The drug is taken orally in a hundred-two hundred milligrams three times during the day.

Among the side effects, manifested against the background of using this medication, allergic reactions are distinguished (they are extremely rare).

Shelf life of the drug is thirty-six months.