The drug "Glybomet" instructions for use refers to a group of hypoglycemic drugs of a combined type. The action of this agent is based on stimulating the secretion of endogenous insulin and a significant increase in the utilization of glucose by muscle tissue. All these processes result in a pronounced synergistic effect, which reduces the risk of developing functional pancreatic insufficiency and the likelihood of undesirable side effects. Among other things, the drug "Glybomet" has a characteristic cardioprotective antiarrhythmic effect and reduces platelet aggregation, which ultimately helps prevent vascular complications of diabetes.
This hypoglycemic drug is produced in the form of round dragees of white hue. Each tablet "Glybomet" contains metformin hydrochloride and glibenclamide, acting as active components. The auxiliary elements are gelatin, MCC, high-dispersion silica , corn starch, magnesium stearate, glycerol, diethylphthalate, cellulose acetate phthalate and talc.
Accept the hypoglycemic drug "Glybomet" instructions for use only in the case of inefficiency of monotherapy with oral medications or diet therapy for the treatment of non-insulin-dependent diabetes mellitus type 2. In addition, the manufacturer recommends prescribing these tablets when the sensitivity to the sulfonylurea agents is reduced due to their prolonged use.
Take the medicine "Glybometh" instructions for use, which is included, categorically prohibits if the patient has an allergic reaction to metformin or glibenclamide, as well as the individual intolerance of any of the auxiliary elements present in the composition. In addition, the list of direct contraindications also includes ketoacidosis, insulin-dependent and latent form of diabetes mellitus, diabetic precoma and coma. Patients with severe pathologies in the liver or kidneys, breathing disorders, severe heart disease, or adrenocortical insufficiency are also advised not to take the hypoglycemic drug "Glybomet". Instructions for use do not recommend the use of these tablets and during fasting, with chronic alcoholism, gangrene, dystrophy or in shock. An established pregnancy or a suspicion of it is also the reason for the cancellation of this medication. Finally, it is not allowed to take this medication for acute bleeding and during lactation.
As for unwanted reactions and possible side effects, the occurrence of which can often be caused by taking Glibometh tablets, the risk of developing hypoglycemia, cholestatic jaundice or hepatitis should be highlighted here first. In addition, some people who use this drug may experience conditions such as vomiting, headache, weakness, sensitivity disorders, urticaria, paresis, muscle cramps, megaloblastic or hemolytic anemia, joint pain.