"Flemoxin solute" (500 mg): instructions for use, description, composition and reviews

The discovery of the antibacterial action of mold fungi, from which penicillin was made, has become a real revolution in medicine. But over time, the pathogenic microflora has adapted to the action of this drug. This forced the scientists to develop synthetic analogues of penicillin, one of which was "Flemoxin Solutab". The instruction, the description of a preparation will help to avoid its negative influence on an organism and by-effects.

The active substance of the drug

The composition of one pill "Flemoxin" includes acid-fast amoxicillin in the form of amoxicillin trihydrate at 125, 250, 500 and 1000 milligrams. This substance has a strong bactericidal effect. Also, drugs with amoxicillin are used against gram-positive and gram-negative bacteria. Sometimes it is used to fight the pathogens of intestinal infections. But in the latter case it is less effective.

Dosage form, composition

What is "Flemoxin Solutab" (500 mg)? The instructions for use describe the preparation of various dosages (125 and 250, 1000 and 500 mg) as oval tablets having a light yellow color. Each tablet on one side is marked with the company logo and digital signage, and on the other hand - with a risk.

When preparing the preparation, auxiliary substances were used, such as single-crystal cellulose, vanillin, dispersible cellulose, magnesium stearate, crospovidone, saccharin, flavors.

The drug is intended for systemic use and is a broad-spectrum medicine.

Pharmacological action on the body

How does the "Flemoxin Solutab" act on the body ? The instruction says that after taking the active ingredient of the drug - amoxicillin - almost all are absorbed in the shortest time (almost 93 percent). And the absorption of the drug is not related to the ingestion of food.

In plasma, the maximum amount of the drug is found one or two hours after the administration. After entering the digestive tract of the drug "Flemoxin Solutab 500 mg" (instruction for use confirms this), the maximum concentration of amoxicillin is noted by researchers after 2 hours. This maximum is 5 μg / ml. If, for any reason, the dose of a medical device decreases or increases, its concentration, respectively, decreases or increases.

Twenty percent of the substance binds to plasma proteins. The therapeutic effect is achieved almost always, since the drug perfectly penetrates into the intraocular fluid, bones, mucous membranes, sputum. In bile, amoxicillin falls into two, and even four times more, than in plasma. In the umbilical cord and amniotic substance, twenty-five to thirty percent of the flemoxin is found from its concentration in the blood of the pregnant woman.

Bad penetration of the active substance through the blood-brain barrier was noted: in the cerebrospinal fluid, its quantity does not exceed twenty percent when used.

The drug is excreted by the kidneys. Eighty percent of the active substance is processed by tubular excretion, the remaining twenty are filtered by glomeruli. Healthy kidneys half amoxicillin an hour and a half. In children up to six months, the elimination half-life is between three and four hours. Dysfunction in the liver does not affect the half-life of the drug.

Pharmacodynamics

"Flemoxin Solutab" (table 500 mg 20 pieces, as well as other dosages of the drug) is an acid-fast bactericidal antibacterial agent with a wide spectrum of action. He is referred to a group of semisynthetic penicillins.

It has a harmful effect on many gram-negative and Gram-positive microorganisms, such as most varieties of streptococci, clostridia, staphylococci, Helicobacteria, coliculus, proteas, salmonella, cholera vibrio.

In what cases is the drug prescribed

In what cases is it prescribed "Flemoxin Solutab" (500 mg)? The instructions for use confirm (this also applies to other dosages of the drug) that the drug is effective:

• At infectious processes in the respiratory tract;
• With infectious ailments of urogenital organs;
• For the treatment of gastrointestinal infections;
• With skin infections and infectious processes in soft tissues.

Who is not allowed to use the drug

"Flemoxin Solutab" (table 500mg n20), the instruction confirms this, it has not only advantages, it also has its contra-indications. This is also true for other dosages of the drug. The drug is not prescribed or prescribed with great care in such cases:

• If the patient has had allergic reactions to it or other antibiotics of this series;
• Patients with lymphatic leukemia or infectious mononucleosis;
• Children under six years of age are administered with caution in the form of a suspension;
• With renal insufficiency;
• With diseases of the gastrointestinal tract, especially those that have arisen due to the use of antibiotics;
• Pregnant women or during lactation are prescribed if the need for the use of the facility exceeds possible risks.

Use of medication by adults

Adults and children who reached ten years and forty kilograms of weight, most often prescribed "Flemoxin Solutab" 500 mg. Instruction for use says that you need to take the drug three times a day. If the infectious process is severe and with complications, a dosage of 0.75 to 1 gram 3 times a day is allowed. Gonorrhea without complications in adults requires the appointment of three grams of the drug at a time. Women are given the same dose again.

Infectious ailments of the stomach, intestines and biliary tract, as well as gynecological diseases of an infectious nature, are treated three times a day in a dosage from one and a half to two grams or four times a gram at one and a half at a time.

Adult people with leptospirosis are treated with a fourfold "Flemoxin Solutaba" solution at 0.5-0.7 grams. Treatment should last from six to twelve days.

Carrying salmonella requires a three-fold application of one and a half to two grams for two to four weeks.

To avoid endocarditis with small surgical interventions, prescribe three to four grams of the drug an hour before the operation. If there is a need for repeated use of the drug, it is prescribed after eight to nine hours in the same dosage.

If the kidneys are disturbed, the interval between doses should be up to 12 hours. For more serious disorders, reduce the dose. If the patient has anuria, the maximum dose should not exceed two grams.

"Flemoxin Solutab" for children - dosage

In most cases, this drug is used as a suspension for children. How is "Flemoxin Solutab" used for children? Dosage and administration depends on the age, weight of the patient, the severity of the infection process. If the child is from five to ten years old, the drug is prescribed in a dose of 250 mg, from two to five years - 125 mg, up to two years, 200 mg are prescribed. In severe cases, 60 mg / kg three times a day are used. The course of treatment with this medicine is six to twelve days.

Newborns and premature babies are given a dose reduction or increase in the interval between doses. For the prevention of endocarditis in small surgical operations, an hour before the procedure is prescribed from one and a half to two grams. If necessary, re-appoint eight to nine hours after surgery.

What side effects may be associated with the use of the drug

Whatever medicine is ideal, from whatever natural components it is created, there are risks of side effects that can affect a patient's condition.

• Allergic reactions can give any dosage of the drug, including "Flemoxin Solutab" 500 mg 20, the price, the instruction of which is almost the same in all used dosage forms. Also, reddening of the skin, eruptions in the form of erythema, angioedema can be observed.
• Occasionally, serum sickness and anaphylactic shock, fever, eosinophilia, arthralgia are noted.
• On the part of the digestive system, nausea, dysbacteriosis, diarrhea, vomiting, changes in taste sensations, pseudomembranous enterocolitis are possible. ALT and AST can increase.
• Changes from the nervous system: there may be violations of sleep, anxiety, depressive phenomena, pain and head spin, episyndrome, impaired consciousness, ataxia.
• Laboratory parameters change: the number of leukocytes, erythrocytes decreases, hemoglobin decreases, neutropenia is noted.
• Possible violation of breathing, increased heart rate, nephritis, vaginal candidiasis, an even greater development of infection (in patients with chronic processes and reduced immunity).
• Overdose of the drug manifests itself in the form of diarrhea, vomiting and nausea, which can lead to a violation of water and electrolyte balance. Assign gastric lavage, saline laxatives, activated charcoal, sometimes - hemodialysis.

"Flemoxin Solutab": reviews, analogues, application

This drug patients are assessed as very effective and relatively safe. It is bioavailable, so the effect from it is very quickly manifested. After the start of treatment, the condition of adults and children improves during the first 24 hours. Depending on the dosage and destination, "Flemoxin Solutab" is very quickly absorbed into the blood. Its operation lasts for eight hours. In this case, the concentration of the substance is noted 15 minutes after use.

As experts note, for children this antibiotic is one of the safest. It is used from early childhood on the prescription of a doctor.

This drug has many synonyms, that is, drugs that are made on the basis of amoxicillin. But there are also some medications with another active substance, but they are used with the same health problems as Flemoxin Solutab. Such preparations are called analogues of the above. The active substances in them are also antibiotics, semisynthetic penicillins. They are used for sepsis, abscesses, infections of the ENT organs and respiratory tract, urinary tract, skin, GI tract, soft tissues and so on.

Such analogs of the drug include:

• "Azlocillin" is an active substance azlocillin.
• "Ampic" - acts with the help of ampicillin.
• "Geopen" is the main substance of carbenicillin.
• "Isipen" is an active substance piperacillin.
• "Penglob" - affects the body with the help of bacampicillin.
• "Flukloxacillin" - the active substance has the same name.

Analogues of the drug, especially antibiotics, should be discussed with the attending physician. This is very important, since only the specialist determines the dosage, the nature of the treatment and the duration. Also, he knows better what kind of active substance is appropriate in a particular case.

Features of the drug, the price

For the majority of patients, indications to the preparation "Flemoxin Solutab", instructions for use, price, description, application features are of interest.

If treatment with a drug is carried out in courses, the kidneys, liver, hematopoiesis should be monitored.

If the patient is sensitive to the penicillin group, there may be cross-allergic manifestations.

If during the treatment there was a slight diarrhea, you should avoid drugs that reduce peristalsis of the intestine. If there is severe diarrhea, you need to seek advice from a medical institution. After the disappearance of clinical manifestations recommended to take "Flemoxin Solutab" for another three to four days.

The drug can reduce the contraceptive effect of oral contraceptives, so during its reception should take care of additional contraception. It also does not work well with aminoglycosides, indirect anticoagulants, methotrexate, digoxin, alopurinol, diuretics, oxyphenbutazone.

Before using it is important to familiarize yourself with the features of the use of the drug Flemoxin Solutab. Instructions for use, reviews will help to avoid undesirable consequences.

Prices for medicines in different cities range from 176 rubles (in Nizhny Novgorod) and up to 228 rubles (in Novosibirsk). In the capital, "Flemoxin Solutab" can be purchased at a price of 191 rubles. In St. Petersburg, it costs an average of 184 rubles.

Do not forget that the instruction for the use of the drug "Flemoxin Solutab" is mainly made for the doctor. And only he can prescribe or cancel a medicine. Avoid self-treatment!