Azithromycin: instructions for use.

The drug "Azithromycin" (Azithromycin) is available in tablets and capsules for two hundred and fifty milligrams of active ingredient. In a blister pack, six pieces per blister.

Pharmacological effects of the drug "Azithromycin" instructions for use describes this way:

It is an antibiotic of a wide range of effects, belongs to the group of macrolides. Has a good bactericidal effect when creating in the pathological focus of its high concentrations. Gram-positive cocci, gram-negative bacteria, some anaerobic microbes, and also some protozoa are sensitive to the preparation.

Pharmacokinetics of the drug "Azithromycin" instructions for use describes this:

It is easily and quickly absorbed from the digestive tract, due to its lipophilicity and resistance to acidic conditions. After the internal intake of five hundred milligrams of the drug, its maximum concentration in the blood is reached after two and a half to three hours and is four tenths of a milligram per liter. Biological availability is thirty seven percent. It is well distributed in the respiratory tract, urogenital tract, prostate gland, skin and soft tissues. And the concentration of azithromycin in the pathological focus is, on average, twenty-four to thirty-four percent higher than in the surrounding healthy tissues. This substance can persist in the inflammatory focus for five to seven days, which makes it possible to apply short treatment courses - for three to five days.

Indications for the appointment of the drug "Azithromycin" instructions for use describes these:

Infectious diseases of ENT organs, upper respiratory tract, scarlet fever, atypical and bacterial pneumonia, bronchitis, impetigo, erysipelas, skin diseases, some infections of the genitourinary system.

The drug "Azithromycin". Application:

Before the appointment, each patient should be tested for sensitivity. The medicine should be taken one hour before meals or two hours after it. You need to take it once a day. For adults, if they have respiratory, soft tissue, skin infections, they are prescribed half a gram on the first day, a quarter of a gram from the second to the fifth day, or half a gram three days (the dose per course is one and a half grams). In acute infectious diseases of the urogenital tract, the drug "Azithromycin" instructions for use gives such doses: once two tablets are half a gram. At the first stage of Lyme disease , two half-gram tablets are prescribed on the first day and one from the second to the fifth days (the course is given three grams of the drug). Children are made appointments, given their body weight. If a child weighs more than ten kilograms, then on the first day is assigned ten milligrams per kilogram, and in the next four - reduce to five. Also, a three-day course of treatment with a single dose of ten milligrams per kilogram is practiced (the dose per course is thirty milligrams per kilogram).

If you need to take "Azithromycin" and drugs that reduce the acidity of gastric juice, between their reception you need to take a break in two hours.

Side effects of the drug "Azithromycin" instructions for use describes the following:

Diarrhea, nausea, abdominal pain, flatulence, vomiting, very rarely - a rash on the skin.

According to the information, which contains the annotation, "Azithromycin" has such contraindications to the application:

Hypersensitivity to the components that are contained in the preparation. In case of serious violations of kidney and liver function, if there are allergies in the history, care should be taken during treatment with this drug. During pregnancy and lactation, appoint only if the benefit from it significantly exceeds the possible risk.