"Arkoksia": reviews of doctors. Anti-inflammatory drug "Arkoksia": price, analogues and contraindications

Unfortunately, a variety of inflammatory diseases are very common, and it is likely that at least once in a lifetime every person has encountered such a problem. Naturally, there are various drugs that help to stop the development of the inflammatory process. And the medicine "Arkoksia" is considered quite good. The doctors' comments about this remedy are positive, as it really helps to cope with the disease, to eliminate pain and fever. So what does it include? In what cases can it be taken? Are there any contraindications? Many patients are interested in answering these questions.

Composition and form of the drug

Two-convex tablets of interesting apple-shaped shape, covered with a film membrane - it is in this form that the drug "Arkoksia" is released. Injections, solutions for oral administration, gels, ointments - these forms of the drug do not exist.

The main active component of the drug is etorikoksib. By the way, in the pharmacy are sold tablets of different colors depending on the amount of active substance - they can be green (60 mg etorikoksiba), white (90 mg) or light green (120 mg).

Naturally, some auxiliary components are present in the composition: magnesium stearate, calcium hydrogenphosphate, croscarmellose sodium and microcrystalline cellulose. The film shell consists of carnauba wax, hypromellose, titanium dioxide, lactose monohydrate, triacetin, aluminum lacquer based on indigo carmine and, of course, basic dyes (opedrai white or green depending on the dosage).

Tablets are placed in convenient blisters for seven pieces. In the pharmacy you can buy packages with one or three such blisters.

Main pharmacological properties

This medicine belongs to the group of non-steroidal anti-inflammatory drugs. Etoricoxib is a substance that selectively inhibits COX-2, which in turn inhibits the synthesis of prostaglandins, blocking the development of the inflammatory process. The drug "Arkoksia" also has a pronounced analgesic and antipyretic effect, but it does not affect the mucosa of the digestive system and the functioning of platelets.

After taking the medicine, it is quickly absorbed, its bioavailability is 100%. The maximum concentration in the blood is observed after 1 hour. The active component binds to plasma proteins by more than 92%. It is excreted from the body mainly through the kidneys, and only 20% of the substances are released with the feces.

Indications for use

In what cases is it expedient to take the medicine "Arkoksia"? Its application is quite wide, as it provides a quick analgesic effect, and also allows to eliminate the inflammatory process. Nevertheless, most often the drug is prescribed to patients suffering from osteoarthritis and rheumatoid arthritis. Indications for use are also pain caused by gouty arthritis and ankylosing spondylitis. In some cases, pills are recommended for people who have recently undergone a dental operation.

Medication "Arkoksia" (tablets): instructions for use and dosage

In no case should you use this medication alone. Only the doctor can prescribe and tell about how to properly take the drug "Arkoksia" (pills). The instruction contains only general recommendations.

Dosage, as a rule, depends on the patient's condition and the variety of his problem. For example, with osteoarthritis, it is most often recommended to take one tablet with a dosage of 60 mg per day, regardless of food intake. The maximum daily dose for patients with spondylitis and rheumatoid arthritis is 90 mg of the active substance. With gouty arthritis, you can take 120 mg per day. The duration of therapy is determined by the attending physician. Nevertheless, the maximum allowable period of treatment is 8-10 days, after which time it is necessary to stop reception at least for a while.

With care, the drug is prescribed for people suffering from liver failure - the daily dose in such cases should not exceed 60 mg.

Are there any contraindications?

Immediately it is worth saying that this drug can not be taken to all categories of patients. The drug has contraindications, with a list of which must be read before the reception:

• Hypersensitivity to the components of the drug, as well as other non-steroidal anti-inflammatory drugs, especially in patients suffering from bronchial asthma and polyposis of the nose;
• Erosive and ulcerative lesions of the mucosa of the digestive tract, gastrointestinal bleeding;
• Inflammatory bowel diseases, including ulcerative colitis and Crohn's disease;
• Bleeding disorders, including hemophilia;
• Severe heart failure;
• Severe forms of renal and hepatic insufficiency;
• Severe ischemic heart disease;
• Period after aortocoronary shunting;
• Persistent arterial hypertension;
• Children's age (the drug is not prescribed for children under 16 years of age);
• Pregnancy, lactation, as well as the period of pregnancy planning.

The drug also has some relative contraindications, in which therapy is possible, but only with the constant supervision of the attending physician. With care, the drug is prescribed for patients suffering from fluid retention in the body, as well as by severe physical illnesses, hypertension and diabetes mellitus. The medicine also can not be combined with alcohol.

Side effects

Many patients ask the question of what complications can lead to the drug "Arkoksia." The doctors' testimonies indicate that patients taking pills rarely complain about any worsening. Nevertheless, adverse reactions are possible. For example, against the background of therapy, an allergic reaction may occur, sometimes even anaphylactic shock. Some patients noted the appearance of nausea, abdominal pain, diarrhea, bloating, eructations, dry mouth.

Possible side effects also include headaches, weakness, confusion, sleep disorders, anxiety, problems with concentration, depressive states, blurred vision, vertigo, tinnitus.

Sometimes there are violations of the respiratory system, in particular cough, as well as nosebleeds. The drug can affect the cardiovascular system, causing increased blood pressure, palpitations, extremely rare - stagnation, circulatory disorders of the brain, hypertensive crisis, myocardial infarction. In some patients, the medicine increases the likelihood of developing infectious diseases of the respiratory and digestive systems.

Overdose: symptoms and treatments

Is an overdose of the drug Arkoksia possible? The doctors' comments and statistical studies indicate that officially such cases were not registered. Even a single dose of 500 mg of active substance, as well as the use of small doses of the drug for three weeks, are not accompanied by serious complications. Overdose can cause aggravation of present side effects from the cardiovascular and digestive systems. Therapy in this case is symptomatic and is aimed at eliminating existing disorders.

Interaction with other drugs

With the simultaneous administration of "Arkoksia" and anticoagulants, you should carefully monitor the international normalized ratio (INR) - the ratio of the prothrombin time of this patient to the mean prothrombin time - especially in the first few days of therapy.

Simultaneous administration of this drug with large doses of acetylsalicylic acid increases the risk of ulcerative lesions of the mucosa of the digestive tract. Simultaneous therapy with tacrolimus and cyclosporins increases the likelihood of developing nephrotoxicity.

The medication can interact with some oral contraceptives, increasing the risk of thromboembolism, so before starting therapy, be sure to tell your doctor about the hormones you take - they may need to be replaced.

Tablets "Arkoksia": analogues and substitutes

This drug is not suitable for every patient for one reason or another. Therefore, many people are interested in the question of what can replace the drug "Arkoksia." Analogues of this tool exist, and there are quite a few of them.

For example, when it comes to analgesia, non-steroidal anti-inflammatory drugs such as Ibuprofen, Nurofen, Diclofenac (by the way, also available in the form of a gel for external use), Ketonal and many others are considered quite popular.

And if you suffer from osteoporosis and other diseases of the musculoskeletal system, then you can choose another substitute. "Arkoksia" is often replaced by such drugs as "Ostalon", "Alendros", "Ost", "Lindron". But remember that only an attending physician can pick up an analogue. Do it yourself categorically is contraindicated.

How much is the medicine?

Many patients are interested in the question of how much the drug "Arkoksia" costs. The price, of course, will depend on some factors. In particular, in consideration it is necessary to take the city of residence, the price policy of the pharmacy, the manufacturer, etc.

So how much will the drug "Arkoksia" cost? The price of a package of seven tablets of 60 mg ranges from 350 to 450 rubles. Three blisters will cost about 1100 rubles. Dosage is another factor on which the cost of the drug "Arkoksia" depends. Tablets of 90 mg cost about 550 rubles for seven pieces. For a package of three blisters, you need to pay about 1300-1400 rubles. Seven tablets with 120 mg of active ingredient cost about 700 rubles.

Feedback from specialists and patients

Of course, many patients are interested in the question of what experts think about the drug "Arkoksia." The doctors' reviews are mostly positive. The fact is that the pills really relieve pain. Moreover, they inhibit the development of the inflammatory process and help normalize body temperature with fever. In addition, the tablets are not as devastating to the liver and digestive system as some other non-steroidal anti-inflammatory drugs. On the other hand, not every patient can take the drug, since there are relatively many contraindications.

Patients for the most part also respond positively about the drug. This tool actually makes the condition easier and relieves soreness, while it works almost throughout the day. Most often, one tablet per day is enough, which is very convenient. Some people have contraindications or side effects, but it is worthwhile to understand that the reaction of the body to these or other medications is individual. To the disadvantages can be attributed a high cost, which not everyone has to afford. On the other hand, one blister, as a rule, is enough for the entire course of treatment.