Treatment of Lymphoma In Israel: Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma (NHL) refers to oncological diseases that affect the lymphatic system.

Risk factors for non-Hodgkin's lymphoma

According to the research, certain risk factors increase the likelihood of NHL development:

• Weakened immunity.
• Infections: HIV, Epstein-Barr virus,, type 1 T-lymphotropic virus, hepatitis C virus, Helicobacter pylori.
• Age (after 60 years).
• Obesity.
• Contact with benzene, insecticides, herbicides.

Signs of non-Hodgkin's lymphoma

• A painful increase in the size of the lymph nodes on the neck, in the groin, in the region of the axillae;
• weight loss;
• temperature increase;
• Excessive night sweats;
• Cough, pain in the chest;
• Fatigue, weakness.

Diagnosis of non-Hodgkin's lymphoma in Israel

• Anamnesis, examination by a doctor.
• Laboratory diagnostics.
• X-ray examination of lymph nodes, the area of the chest.
• Biopsy (excisional biopsy, incisional biopsy).

The most common types of NHL: follicular lymphoma and diffuse B-cell lymphoma.

Depending on the growth rate of lymphoma are grouped into:

• Non-aggressive or lazy with a low degree of malignancy.
• Aggressive lymphomas that cause severe clinical manifestations.

To determine the stage of non-Hodgkin's lymphoma and to select the best treatment option, additional tests are performed:

• A bone marrow biopsy.
• CT scan.
• MRI.
• PET-CT.

Non-Hodgkin's lymphoma has four stages of development.

Treatment of non-Hodgkin's lymphoma in Israel

The choice of course of treatment for lymphoma in Israel will depend on the type of disease, stage, rate of growth of the tumor process, the age of the patient and his individual characteristics.

Active surveillance

This period, when there are no symptoms, is a monitoring of the patient's condition, control every three months.

Chemotherapy

Chemotherapy is a systemic treatment, the drug, getting into the blood, covers the entire body and destroys malignant cells. Therapy can be carried out intravenously, orally, by puncture into the cerebrospinal fluid.

Chemotherapy consists of cycles of treatment and rest. The length of rest and the number of cycles are determined by the stage of lymphoma and chemotherapy:

• With nonaggressive lymphoma - a combination of CVP drugs (prednisolone, vincristine, cyclophosphamide), preparations Fludarabine and Chlorambucil;
• For the treatment of aggressive lymphomas - a combination of CHOP drugs (adriamycin, vincristine, cyclophosphamide and prednisolone).

Target therapy

It destroys the cells of lymphoma, slows down the rate of their development. Highly effective in the treatment of lymphoma monoclonal antibodies: MabThera, Zevalin, Alemtuzumab.

In the treatment of NHL in the clinics of Israel used interferon.

Treatment of lymphoma in Israel: radiation therapy

Ionizing radiation of radiation therapy destroys cancer cells. Radiotherapy is prescribed to reduce the tumor, destroy the residual after surgery, to aid in the therapy of pain.

Stem cell transplantation

If relapses of lymphoma are observed, high-dose chemotherapy, radiotherapy, or both are used. However, high doses of drugs also destroy the human hematopoietic system. To restore it, the stem cells are transplanted.