The preparation is "Prestarium". Instructions for use

The preparation "Prestarium" instructions for use describes it as an antihypertensive agent. The medication is available in the form of tablets. Active active substance of the drug is arginine perindopril. Auxiliary components are lactose monohydrate, magnesium stearate, colloidal hydrophobic dioxide, sodium carboxymethyl starch, glycerol, hypromellose, macrogol 6000 and titanium dioxide.

The medication "Prestarium", the instruction for use informs, helps to eliminate arterial hypertension. As a result of therapy, there is a decrease in the indices of both diastolic and systolic pressure (in the standing and lying position). Stabilization of blood pressure occurs in a short time.

It is specially noted that the addiction to this drug does not develop, and the completion of therapy does not entail the onset of withdrawal syndrome.

The active active substance of the drug "Prestarium" (instructions for use contains this information) is able to produce a vasodilating effect, restore the elasticity of large arteries and the structure of small ones. In addition, the drug reduces the manifestation of hypertrophy in the left ventricle.

The drug "Prestarium" after getting into the gastrointestinal tract is rapidly absorbed from it. The maximum content in the blood is fixed at least an hour after ingestion.

The considered pharmaceutical agent should be taken shortly before meals, as taking during eating reduces its bioavailability.

The drug is excreted mainly by the kidneys. The half-life of the drug is seventeen hours. It has been established that in patients of advanced age (as well as in those suffering from renal and heart failure) perindoprilat leaves the body much more slowly.

The drug "Prestarium", the instruction for use informs, is shown with arterial hypertension, chronic heart failure, prevention of recurrent stroke, and also to minimize the risk of cardiovascular complications.

Dosage recommendations

The drug should be taken 1 time a day before eating.

Pharmaceutical preparation "Prestarium". Side effects

· On the part of the urinary system - renal failure in acute form and malfunctioning of the kidneys.

· Dysfunctions of the respiratory system - pneumonia, cough, rhinitis, bronchospasm, angioneurotic edema are also noted.

· On the part of the digestive system, there may be a violation of taste, a decrease in appetite, abdominal discomfort, vomiting or nausea, loose stools or constipation, pancreatitis.

· Among allergic reactions - itching, rash, urticaria, erythema (multiforme).

· The following failures in the functioning of the central nervous system were recorded: ringing in the ears, dizziness, muscle cramps, paresthesia, headaches, insomnia, mood swings, asthenia.

· From the cardiovascular system - secondary severe arterial hypertension, a sharp drop in blood pressure, extremely rarely - myocardial infarction, arrhythmia, stroke, angina.

Contraindications to the use of the medicament in question are the following:

- waiting period for the child;

- breast-feeding;

- hypersensitivity to other ACE inhibitors;

- individual sensitivity to the substances included in the preparation;

- galactosemia, lactose insufficiency.

When an overdose of the drug may affect the electrolyte balance, the development of kidney failure, tachycardia, bradycardia, the emergence of anxiety, cough, shock.