The drug 'Pronoran'. Instructions for use

The drug "Pronoran" (an analog of such drugs as "Tasmar", "Selegilin", "Parkon" and others) is included in the category of anti-Parkinsonics. The active ingredient is pyribedil. The medication is available in tablet form.

After ingestion, the active ingredient is rapidly absorbed from the digestive system. The maximum concentration of the drug is noted after an hour. Slow dissolution of the "Pronoran" tablet provides a gradual release of the active ingredient. The therapeutic concentration of the drug persists for twenty-four hours.

Characterizing the mechanism of action of the drug "Pronoran", the instruction for use indicates its ability to exert a vasodilating effect (increase blood circulation in the vessels in the lower limbs). The drug provokes dopaminergic stimulation of the electrical activity of the cortex both during sleep and during wakefulness, and also affects various functions that are controlled by dopamine.

The drug "Pronoran" instruction for use recommends for Parkinson's disease as a mono drug in forms complicated by tremor, or as part of complex therapy (again or at the beginning of the disease in forms that are accompanied by tremor). The drug is prescribed as an additional symptomatic treatment for the disorder of cognitive function of the chronic course and neurosensory insufficiency against the background of aging (including memory and attention violations). Indications include symptoms of ophthalmic diseases of ischemic nature (including lowering visual acuity, reducing contrast, narrowing the visual field). As an additional therapy, the drug "Pronoran" instructions for use recommends with intermittent claudication associated with obliterating lesions of the lower limbs.

No medication is prescribed for collapse, hypersensitivity to components, acute myocardial infarction and other cardiovascular pathologies. The drug "Pronoran" instruction for use does not recommend taking simultaneously with neuroleptics, which have strong antipsychotic properties (except for the drug "Clozapine").

Due to the lack of reliable data on the efficacy and safety of the use of the drug during pregnancy and lactation, it is not prescribed for pregnant and lactating women.

Taking the drug "Pronoran" can cause flatulence, vomiting, nausea. These manifestations are eliminated, usually after a dose adjustment. In some cases, the drug may provoke drowsiness, mental disorders (confusion, anxiety). As a rule, the symptoms are eliminated after the drug is discontinued. Very rarely there may be lability of BP or orthostatic hypotension, an allergic reaction. The drug "Pronoran" (reviews of patients and specialists testify about this) is transferred in most cases well.

The medicine is prescribed after eating, inside. Tablets do not need to be crushed. The drug is swallowed whole, squeezed in sufficient volume with water.

For all of these indications (except for Parkinson's disease), the recommended dose is one tablet (50 milligrams). Take the drug once a day. If necessary (as agreed with the doctor), it is allowed to increase the dosage by half (fifty milligrams twice a day).

As monotherapy for Parkinson's disease, 150-250 milligrams (three to five tablets) per day are prescribed. As part of a combination therapy, the dosage of the drug "Pronoran" is reduced to 100-150 milligrams per day (up to two to three tablets).

If a patient has arterial hypertension, an antihypertensive treatment is prescribed simultaneously with taking the medication.

The use of the drug "Pronoran" should be monitored by a specialist.