The drug "Ovitrel": instructions for use, analogues and reviews

The birth of children is the main purpose of a woman, programmed by nature. However, modern ecology, persistent nervous stress, stress, congestion at work or other problems can provoke infertility in girls. In this case it is necessary to help the body with medical preparations. For example, doctors can prescribe such a tool as "Ovitrel". Instructions for use of this medication will be set out below.

general characteristics

This substance is a recombinant human chorionic gonadotropin, which is no different from the natural one. This drug is hormonal.

It is used in gynecology and repair the preparation "Ovitrel". Instruction for the use of the drug is the main document that the patient should familiarize with. This is an imported remedy. It is produced in Italy.

Sold medicine only by prescription. Hormonal therapy can not be dealt with on its own, since the patient can not know the nuances of the action of the substance. In addition, the doctor must make the necessary tests and find out whether the drug is suitable for the patient.

Composition and form of release

If you are interested in what "Ovitrel" consists of, the instructions for use point to its components:

1. The main active ingredient is chorionic gonadotropin.

2. Mannitol.

3. Methionine.

4. Poloxamer 188.

5. Sodium hydroxide.

6. Phosphoric acid.

7. Distilled water.

As for the forms of output, there are only two of them:

- Fluid . It can be transparent or slightly yellow. She is placed in a glass syringe. It also has a needle, a rubber gasket and a protective cap.

- Powder . It is in a glass bottle sealed with a rubber lid. In addition, complete with the drug is a solution for diluting the powder. The package may contain one, two or 10 bottles of the product.

It should be noted that the syringe is used only once.

Pharmacological action and interaction with other drugs

If the doctor has appointed you a remedy like Ovitrel, the instructions for use will help you understand the peculiarities of his action. The substance provokes the reduction division of the egg, rupture of the follicle and the onset of ovulation, the formation of the yellow body, as well as the production of hormones that support pregnancy - estradiol and progesterone.

Such properties of the drug contribute to conception, fixation of a fertilized egg in the uterine cavity, normal development of the fetus.

The drug "Ovitrel" has a rather high level of bioavailability - 40%. The half-life of the substance from the body is approximately 30 hours.

As for the interaction of the drug with other drugs, there is no information on this matter. However, if during the hormone therapy a woman takes any more funds, she must tell the doctor about it.

Indications

If a woman has problems with conception, she can be prescribed the drug "Ovitrel". Instructions for use (photo means you can see in the article) will tell you about the indications for the prescription of this medication. So, take the substance is necessary in the case of anovulatory or oligo-ovulatory infertility. That is, if a woman of childbearing age is completely absent or pathologically rarely occurs ovulation, without which pregnancy can not occur.

Most often, the drug is used during in vitro fertilization to stimulate the final maturation of the follicles and the formation of a yellow body after it. Often, the remedy is also prescribed for those women who have difficulties with the onset of a natural pregnancy, but infertility is not confirmed.

Contraindications to use

Instructions for the use of the drug "Ovitrel" provides for certain limitations and contraindications:

- Too high sensitivity to one or more components of the drug.

- Malignant or benign tumors of internal genital organs, hypothalamus and pituitary gland.

- Neoplasms or cysts on the ovaries that are not associated with polycystic disease.

- Vaginal bleeding, the nature of which can not be determined.

- Breast cancer.

- Ectopic pregnancy, which was detected in 3 previous stimulations of the month.

- The period of breastfeeding or pregnancy.

- Thromboembolism of any vessels.

- Primary ovarian failure.

- Fibromioma of the uterus.

- Menopause.

- Severe congenital physical defects of internal and external genital organs, which can not be compatible with pregnancy.

When prescribing the drug should be particularly spicy, if the patient has a serious systemic disease, which during pregnancy can go to the stage of exacerbation.

Possible adverse reactions

"Ovitrel" (the description of the drug you have already read) can provoke the onset of side effects. Among them may be such:

- Pain in the abdomen, nausea and vomiting, and in some cases diarrhea can also occur.

- Soreness of the chest, ovarian hyperstimulation syndrome.

- Increased irritability, sensitivity, headache, unreasonable anxiety, fast fatigue.

- A slight reaction to the skin in the form of a rash.

- Puffiness and pain at the injection site.

- Light allergy and fatigue.

As you can see, these side effects are not too strong and can be quickly eliminated. Careful to be with hyperstimulation. If this happens, then, it may be necessary to suspend the drug for a while.

Dosing features and rules for the administration of the drug

Scientists have long proven that the most effective in the treatment of female infertility is the drug "Ovitrel." The instruction (the drug description will help you determine the need for its purchase) provides for such a regimen for IVF: once 250 μg of substance is administered subcutaneously 1-2 days after the last administration of FSH.

With anovulatory or oligovulatory infertility for induction of ovulation and luteinization at the end of stimulation of follicle growth, the drug is also administered once 24-48 hours after reaching the optimum level of follicle development. It is recommended to have sexual intercourse on the day of drug administration and the next day.

If you use the tool yourself, you must follow certain rules for its introduction:

1. During the injection, antiseptic agents should be used.

2. To begin with, spread some cotton swabs and a syringe (ready-made) on a clean surface. If necessary, the substance must first be diluted. The place of injection should be rubbed with alcohol.

3. Then immediately inject into the abdomen or the front of the thigh. In this case, the skin should be tightened as much as possible. Note that the angle of needle entry should be 45 or 90 degrees. You can not get the medicine into a vein, so be as careful as possible. Enter the fluid slowly until the syringe is completely empty. Then in a circular motion with a tampon, massage the injection site.

4. After the injection, the syringe must be disposed of. Even if a small amount of substance remains in it, it is no longer possible to use it again.

What analogies can I use?

It must be said that the cost of this foreign drug is quite high. For example, one dose of undiluted powder has a price of 2300 rubles. The ready syringe costs almost 2600 rubles. The course of therapy involves more than one injection. This forces patients to look for other options.

If you can not afford the drug "Ovitrel", the instruction (analogues can have a lower cost with the same effect) tells about such possible substitutes: "Pregnil", "Menogon", "Menopur", "Merional", "Louveris", "Fallitrop "," Echokhimulin "," Pergoveris ".

Term and conditions of storage

So, the drug should be in the refrigerator at a temperature of 2-8 degrees. Do not freeze the product. Shelf life of the substance is 2 years, and the solution for breeding is 3 years.

If the drug is not in the refrigerator, then the ambient temperature should not exceed 25 degrees. In such circumstances, Ovitrel can only be stored for 1 month. If during this time it has not been applied, then it can already be discarded.

Reviews and specific instructions for use

In principle, you can note a good opinion about the drug among users. They indicate the effectiveness of the tool. If you follow the instructions, this drug does not cause any adverse reactions. Although some women note pain in the abdomen, headache and nausea.

Before you start taking this medication, you need to carefully examine both partners and establish the true cause of infertility. At the time of prescribing the substance, you need to be careful if there is adrenal insufficiency and hypothyroidism.

Each vial or syringe can be used only once. During stimulation, the level of estradiol in the blood should be constantly monitored to prevent OHSS, and regular ultrasound should be performed. During the therapy, it is possible to strengthen the functioning of the thyroid gland.

Please note that taking alcohol 24 hours before the introduction of the drug and within 14 days after the procedure is categorically impossible.

After the injection, you can safely drive the car, because the reaction speed and attention means does not affect. It should be remembered: if you need the drug "Ovitrel", the instruction (the testimony you already know) is only for informational purposes. Only a doctor can prescribe it.

That's all that can be said on the topic: "Ovitrel, instructions for use, analogues." Be Healthy!