Antibodies to thyroglobulin

The thyroid gland is a hormone-producing organ, which is the link in many metabolic processes in the body. It is worth noting that the functioning of the body is a whole chain of physical and chemical transformations, the main purpose of which is life.

Therefore, if one link is interrupted, then the violations will be in the whole chain. This information needs to be understood in order to realize the importance of such a small organ as the thyroid gland and its hormones.

Now it is known that thyroglobulin is a protein from which two main hormone glands are formed - T3 and T4. Antibodies to thyroglobulin - the main indicator of the quantitative ratio of hormones, and hence the work of the gland as a whole. Interesting is the fact that the diseases of this body have become known more recently, more precisely, to diagnose them earlier simply could not. That is why the method of diagnosing the number of hormones has become a new achievement in medicine.

Antibodies to thyroglobulin are determined if the patient is suspected of having a thyroid pathology, or a violation of the work of target organs. However, there is a breakdown by classes of antibodies, each of which indicates a process (acute, chronic or transferred). Thus, the definition of AT requires not only special equipment, but also a sufficient level of qualification of the doctor, in order to correctly interpret the data.

Analysis for antibodies to thyroglobulin is carried out in a special laboratory, in which there is all the necessary equipment. To do this, the patient takes blood from the vein, preferably on an empty stomach and outside the intake of medicines. The analysis is done within one working day, so the patient can be prescribed the necessary therapy on the same day.

Antibodies to thyroglobulin are determined when:

- chronic thyroiditis of Hashimoto type;

-hyperthyroidism in newborns;

-hyperthyroidism and its differential diagnosis;

-Eutireoid craw;

- diffuse toxic goiter.

There are certain limits to the fluctuation of hormones in the blood, according to the time of day, the patient's sex, his age, and other factors. However, it is necessary to understand that the upper and lower limits of the norm are a sign of pathology, i.e. In the body there are already any violations that can develop into more serious diseases.

When antibodies to thyroglobulin are determined, the norm is considered in international units of action per liter and is:> 190 IU / ml. The so-called borderline result can be considered the quantitative content of antibodies within the range of 60-190 IU / ml. These indicators are the most transitional from a healthy state to a disease. Pathology is considered the content of AT less than 60 IU / ml. Patients with such values of the level of antibodies are sent to a follow-up for the final diagnosis.

Antibodies to thyroglobulin are increased if the patient has a Hashimoto goiter or a chronic idiopathic thyroiditis. In the analyzes of such a person, predominantly immunoglobulins of class G will prevail, and in the general blood test, a shift of the leukocyte formula to the left and an increase in the rate of erythrocyte sedimentation can be detected.

Similarly, the amount of AT increases with idiopathic hypothyroidism and Based's disease (decrease in the number of thyroid hormones). Thyroid cancer, goiter and other pathological conditions can also increase the titre of AT to thyroglobulin in the analysis of venous blood.

A distinctive feature can be considered the fact that this reaction with a tendency to increase the AT to protein thyroglobulin is also characteristic of Down's disease, which sometimes can not be diagnosed at an early pregnancy.